SARS-CoV-2 Spike-Membrane Recombinant Fusion Protein, His Tag
Figure 1. SARS-CoV-2 Spike-Membrane Recombinant Fusion Protein, His Tag on SDS-PAGE under reducing condition.
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| Amount : | 50 µg |
| Purification : | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| AA sequence : | S protein (Lys310-Leu560) Membrane protein(Met1-Lys15) 6×His |
| Uniprot ID : | P0DTC2 |
| Alternative Name : | S protein, M protein, COVID-19 |
Expression Host : HEK293
The protein has a predicted molecular mass of 31.2 kDa after removal of the signal peptide.
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
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