SARS-CoV-2 Nucleocapsid Antibody (Clone: 1G5)
Fig.1: Western Blot analysis: 2019 nCOV N protein were subjected to SDS PAGE followed by western blot with 29-1006 (anti- 2019 nCOV N protein Monoclonal antibody) at dilution of 1µg/ml.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1 |
| Purification : | Protein A |
| Content : | CB buffer, pH 7.5 |
| Storage condition : | CB buffer, pH 7.5, -20℃ for 12 months(Avoid repeated freeze / thaw cycles. |
| Alternative Name : | Anti-coronavirus NP Antibody; Anti-coronavirus Nucleocapsid Antibody; Anti-coronavirus Nucleoprotein Antibody; Anti-cov np Antibody; Anti-ncov NP Antibody; Anti-NCP-CoV Nucleocapsid Antibody; Anti-novel coronavirus NP Antibody; Anti-novel coronavirus Nucleocapsid Antibody; Anti-novel coronavirus Nucleoprotein Antibody; Anti-np Antibody; Anti-nucleocapsid Antibody; Anti-COVID-19 Nucleoprotein Antibody |
| Immunogen Information : | 2019 nCOV N protein. |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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