ROR-gamma(t) Reporter Assay

ABEOMICS custom ROR-gamma T reporter assay utilizes the proprietary ROR-gamma T reporter cell line system. RAR-related orphan receptor gamma T (ROR-gamma T) is a nuclear receptor expressed primarily in Th17 cells and drives Th17 cell differentiation. ROR-gamma T reporter system is designed to monitor the ROR-gamma T promoter activity. ROR-gamma T reporter assay services include screening of agonists/antagonists that affect the ROR-gamma T induction, EC50/IC50 evaluation of those agonists/inhibitors/inhibitory antibodies, and functional analysis of ROR-gamma T induction-related signaling pathways. Assay results will contain a written report and downloadable Excel- or Prism-based data.