Recombinant Rat SDF-1Beta (CXCL12)(Discontinued)

Product code: 32-20225

Reactivity : Human, Rat

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Amount : 10 µg
Purification : Purity: >= 95% by SDS-PAGE gel and HPLC analyses.
AA sequence : KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
Alternative Name : Stromal-Cell Derived Factor-1, CXCL12, PBSF
Source:E.coli
SDF-1Alpha and Beta are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1Alpha and Beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1Alpha and Beta contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1Beta protein, produced by an N-terminal truncation of two additional amino acids, after removal of the signal sequence, contains 72 amino acid residues. Recombinant Rat SDF-1Beta is an 8.4 kDa protein containing 72 amino acid residues.

Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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