Recombinant Rabbit Monoclonal Antibody to mTOR (Clone: RM274)(Discontinued)

Product code: 10-9632

Clone name : RM274
Clonality : Monoclonal
Application : WB, IHC
Reactivity : Human, Mouse , Rat

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Purification : Protein A affinity purified from an animal origin-free culture supernatant
Content : Antibody in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Storage condition : Store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : MTOR
Gene ID : 2475
Uniprot ID : P42345
Alternative Name : MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Immunogen Information : A peptide corresponding to human serine/threonine-protein kinase mTOR.

Clone RM274 reacts to human serine/threonine-protein kinase mTOR. This antibody may also react to mouse or rat mTOR, as predicted by immunogen homology. Immunohistochemistry (IHC): 1:500-1:1000 dilution; Western Blot (WB): 1:1000-1:2000 dilution.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Endoplasmic reticulum membrane, Golgi apparatus membrane, Mitochondrion outer membrane, Lysosome, Cytoplasm, Nucleus, Microsome membrane
Post transnational modification: Autophosphorylates when part of mTORC1 or mTORC2. Phosphorylation at Ser-1261, Ser-2159 and Thr-2164 promotes autophosphorylation. Phosphorylation in the kinase domain modulates the interactions of MTOR with RPTOR and PRAS40 and leads to increased intrinsic mTORC1 kinase activity. Phosphorylation at Thr-2173 in the ATP-binding region by AKT1 strongly reduces kinase activity.
Tissue Specificity: Expressed in numerous tissues, with highest levels in testis.
BioGrid: 108757. 216 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products