Recombinant Rabbit Monoclonal Antibody to Histone H2B (Clone: RM230)(Discontinued)
Figure 1: Western Blot of recombinant Histone H2A, H2B, the whole cell lysates of HeLa, A375, SK-MEL-2, A431, and K562, using Clone: RM230 at 0.2 µg/ml
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A affinity purified from an animal origin-free culture supernatant |
| Content : | 1 mg/ml in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Storage condition : | Store at -20°C. Avoid repeated freeze and thaw cycles. |
Clone RM230 reacts to the Histone H2B protein, independent of post-translational modifications. No cross reactivity with other histone proteins. Western Blot: 0.1 µg/ml - 1 µg/ml; ICC: 0.5 µg/ml - 1 µg/ml; ELISA: 0.2 µg/ml - 1 µg/ml; Multiplex: 0.2 µg/ml - 1 µg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Chromosome |
| Post transnational modification: | Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes. |
| BioGrid: | 114460. 29 interactions. |
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