Recombinant Rabbit Monoclonal Antibody to CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker)(Clone : Ki-1/1747R)

Product code: 12-1051

Clone name : Ki-1/1747R
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Purified Ab with BSA and Azide at 200ug/ml
Content : 200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : TNFRSF8
Gene ID : 943
Uniprot ID : P28908
Alternative Name : CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
Immunogen Information : Recombinant human full-length TNFRSF8 protein
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 8.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Phosphorylated on serine and tyrosine residues.
BioGrid: 107381. 30 interactions.
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