Recombinant Rabbit Monoclonal Antibody to Androgen Receptor (N-Terminal) (Clone: RM254)(Discontinued)
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded 22RV1 cells sections using anti- Androgen Receptor (N-term) rabbit monoclonal antibody (Clone: RM254) at a 1:2500 dilution.
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Purification : | Protein A affinity purified from an animal origin-free culture supernatant |
| Content : | Antibody in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Storage condition : | Store at -20°C. Avoid repeated freeze and thaw cycles. |
Clone RM254 reacts to full length androgen receptor and splice variants. Immunohistochemistry (IHC): 1:1000 – 1:2500 dilution; Western Blot (WB): 1:100 – 1:1000 dilution.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm |
| Post transnational modification: | Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation. |
| Tissue Specificity: | Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107). |
| BioGrid: | 106862. 284 interactions. |
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