Recombinant Rabbit Monoclonal Antibody to Acetyl-Histone H2B (Lys23) (Clone: RM260)(Discontinued)

Product code: 10-9582

Clone name : RM260
Clonality : Monoclonal
Application : WB, ELISA, Multiplex, ICC
Reactivity : Human

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A affinity purified from an animal origin-free culture supernatant
Content : 1 mg/ml in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Storage condition : Store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : HIST1H2BB
Gene ID : 3018
Uniprot ID : P33778
Alternative Name : HIST1H2BB, H2BFF
Immunogen Information : An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys23).

Clone RM260 reacts to Histone H2B acetylated at Lysine 23 (K23ac). No cross reactivity with other acetylated Lysines in histones. Western Blot: 0.5 µg/ml – 2 µg/ml; ICC: 0.5 µg/ml - 2 µg/ml; ELISA: 0.2 µg/ml - 1 µg/ml; Multiplex: 0.1 µg/ml – 0.5 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Chromosome
Post transnational modification: Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
BioGrid: 109271. 62 interactions.
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