Recombinant Murine IL-9(Discontinued)

Product code: 32-20458

Reactivity : Human, Mouse

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity:>= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP
Alternative Name : p40 cytokine, T-cell growth factor p40
Source:E.coli
IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes.  IL-9 enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia cell lines.  Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease.  Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells.  Recombinant Murine IL-9 is a 14.3 kDa protein of 127 amino acid residues, including 10 cysteine residues that are fully conserved between the human murine proteins.

The ED50 as determined by the dose-dependent proliferation of human MO7e cells is <=0.5 ng/ml, corresponding to a specific activity of>= 2 x 106 units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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