Recombinant Murine IL-3(Discontinued)
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
Amount : | 10 µg |
Purification : | Purity: >= 98% by SDS-PAGE gel and HPLC analyses. |
Content : | This recombinant protein is supplied in lyophilized form. |
AA sequence : | MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC |
Alternative Name : | MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor |
Source:E.coliIL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes s µggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is <= 0.05 ng/ml, corresponding to a specific activity of >= 2 x 107units/mg.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
There are currently no product reviews
|