Recombinant Murine IL-3(Discontinued)

Product code: 32-20217

Reactivity : Human, Monkey, Mouse, Rat

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC
Alternative Name : MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
Source:E.coli
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.  Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity.  Its ability to activate monocytes s µggests that IL-3 may have additional immunoregulatory roles.  Many of the IL-3 activities depend upon co-stimulation with other cytokines.  IL-3 is a species-specific, variably glycosylated cytokine.  Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is <= 0.05 ng/ml, corresponding to a specific activity of >= 2 x 107units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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