Recombinant Murine IFN-Gamma(Discontinued)

Product code: 32-20176

Reactivity : Cow, Human, Rabbit, Rat

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Alternative Name : Immune Interferon, type II interferon, T cell interferon, MAF
Source:E.coli
IFN-Gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes, as well as activated NK cells.  IFN-Gamma receptors are present in most immune cells, which respond to IFN-Gamma signaling by increasing the surface expression of class I MHC proteins.  This promotes the presentation of antigen to T-helper (CD4+) cells.  IFN-Gamma signaling in antigen-presenting, cells and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response.  Additionally, IFN-Gamma stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.  Human IFN-Gamma is species-specific and is biologically active only in human and primate cells.  Recombinant Murine IFN-Gamma is a 15.6 kDa protein containing 134 amino acid residues.

Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is <= 0.2 ng/ml, corresponding to a specific activity of >= 5 x 106units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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