Recombinant Murine gAcrp30(Discontinued)

Product code: 32-20128

Reactivity : Mouse

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Amount : 25 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MKGEPGEAAY MYRSAFSVGL ETRVTVPNVP IRFTKIFYNQ QNHYDGSTGK FYCNIPGLYY FSYHITVYMK DVKVSLFKKD KAVLFTYDQY QEKNVDQASG SVLLHLEVGD QVWLQVYGDG DHNGLYADNV NDSTFTGFLL YHDTN
Alternative Name : APM-1, gad, globular domain of Acrp30
Source:E.coli
gAcrp30 is a naturally occurring globular protein obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and named AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant Murine gAcrp30 is a 16.6 kDa protein consisting of 145 amino acid residues.

Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED50 for this effect is <= 15 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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