Recombinant Mouse Triphosphate Diphosphohydrolase 1/ENTPD1/CD39 (C-6His)
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| Amount : | 50 µg |
| Content : | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| AA sequence : | Recombinant Mouse Ectonucleoside Triphosphate Diphosphohydrolase 1 is produced by our Mammalian expression system and the target gene encoding Thr38-Ile478 is expressed with a 6His tag at the C-terminus. |
| Alternative Name : | Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39 |
Source : Human Cells;
Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker. But it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1 hydrolyzes the Beta-andgamma phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling. NTPDase-1 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases.
Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker. But it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1 hydrolyzes the Beta-andgamma phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling. NTPDase-1 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases.
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