Recombinant Mouse TREML2/TLT-2 (C-6His)

Product code: 32-8734

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  •   10 µg

  •  50 µg

  • $344.00 

  • $440.00 

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Amount : 50 µg
Content : Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Storage condition : Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
AA sequence : HSNENLYRKVWRREGETLSVQCSYKNRRNLVEAKSWCKVKKKKCDHNFTRSWVRGPSYSLRDDAKVKVVRITMEALRVQDSGRYWCMRNTAGHFYPLVGFQLEVYPALTTERNVPHTHLTNTPMDGFVTTGQVHISDPHAPFTSDVTMFTSEVTMFTSGLLTLASGTTTPTPVTGYSFIDTSGTVTEPERNTESQPATLSPSNARSFSADPVTTSTMSRHQSSSLSTTGTCHPLTPNRSQETYIPAHHHHHH
Gene : Treml2
Gene ID : 328833
Uniprot ID : Q2LA85
Source: Human Cells.
MW :28.4kD.
Recombinant Mouse TREML2 is produced by our Mammalian expression system and the target gene encoding His25-Ala270 is expressed with a 6His tag at the C-terminus. Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.

Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Tissue Specificity: Detected in B-lymphocytes and macrophages. Detected in spleen, lymph nodes, blood, bone marrow and cells from the peritoneal cavity (at protein level).
BioGrid: 236663. 1 interactions.
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