Recombinant Mouse Tacstd2/Trop2(C-6His)
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| Amount : | 50 µg |
| Content : | Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4. |
| AA sequence : | Recombinant Mouse Tumor-associated calcium signal transducer 2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus. |
| Alternative Name : | Tumor-associated calcium signal transducer 2;Tacstd2;Trop2;Cell surface glycoprotein Trop-2 |
Source : Human Cells;
Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
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