Recombinant Mouse IL17RA Protein, His Tag
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| Amount : | 50 µg |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | Q60943 |
| Alternative Name : | IL-17RA, CD217 |
Molecular Characterization: Mouse IL17RA(Ser32-Trp322) 6×His tag
Molecular weight: The protein has a predicted molecular mass of 34.1kDa after removal of the signal peptide. The apparent molecular mass of mIL17RA-His is approximately 55-70 kDa due to glycosylation.
Description: Recombinant mouse IL17RA protein with C-terminal 6×His tag
Receptor for IL17A (PubMed: 17911633, PubMed: 20554964, PubMed: 8777726). Receptor for IL17F (PubMed: 17911633, PubMed: 20554964). Binds to IL17A with higher affinity than to IL17F (PubMed: 17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed: 21993848, PubMed: 21993849, PubMed: 21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).[UniProtKB/Swiss-Prot Function]
Molecular weight: The protein has a predicted molecular mass of 34.1kDa after removal of the signal peptide. The apparent molecular mass of mIL17RA-His is approximately 55-70 kDa due to glycosylation.
Description: Recombinant mouse IL17RA protein with C-terminal 6×His tag
Receptor for IL17A (PubMed: 17911633, PubMed: 20554964, PubMed: 8777726). Receptor for IL17F (PubMed: 17911633, PubMed: 20554964). Binds to IL17A with higher affinity than to IL17F (PubMed: 17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed: 21993848, PubMed: 21993849, PubMed: 21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).[UniProtKB/Swiss-Prot Function]
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