Recombinant Mouse Granzyme D/GZMD (C-6His)(Discontinued)

Product code: 32-8752

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Amount : 50 µg
Content : Lyophilized from a 0.2 µm filtered solution of 20mM HEPES, 150mM NaCl, pH7.4.
Storage condition : Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
AA sequence : IIGGHVVKPHSRPYMAFVMSVDIKGNRIYCGGFLIQDDFVLTAAHCKNSSVQSSMTVTLGAHNITAKEETQQIIPVAKDIPHPDYNATIFYSDIMLLKLESKAKRTKAVRPLKLPRSNARVKPGDVCSVAGWGSRSINDTKASARLREVQLVIQEDEECKKRFRYYTETTEICAGDLKKIKTPFKGDSGGPLVCDNQAYGLFAYAKNGTISSGIFTKVVHFLPWISWNMKLLVDHHHHHH
Gene : Gzmd
Gene ID : 14941
Uniprot ID : P11033
Source: Human Cells.
MW :26.8kD.
Recombinant Mouse Granzyme D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu252 is expressed with a 6His tag at the C-terminus. Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.

Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasmic granule
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