Recombinant Mouse Catenin beta-1/ beta-Catenin/CTNNB1 (C-6His)(Discontinued)
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| Amount : | 50 µg |
| Content : | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
| Storage condition : | Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months. |
| AA sequence : | MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEALGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDLVDHHHHHH |
Source: Human Cells.
MW :86.5kD.
Recombinant Mouse Catenin beta-1 is produced by our Mammalian expression system and the target gene encoding Met1-Leu781 is expressed with a 6His tag at the C-terminus. Catenin beta-1, also called CTNNB1, is a cytoplasm and nucleus protein of the beta-catenin family. CTNNB1 is a key component of the cadherin cell-cell adhesion system that serves important roles in cell development, differentiation, maintenance of normal tissue architecture, and when dysregulated contributes to tumor invasion and metastasis. The mutations and overexpression of CTNNB1 are associated with many cancers, such as hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors, ovarian and endometrial cancer. CTNNB1 is involved in signal transduction through the Wnt pathway, and is widely expressed in many tissues.
MW :86.5kD.
Recombinant Mouse Catenin beta-1 is produced by our Mammalian expression system and the target gene encoding Met1-Leu781 is expressed with a 6His tag at the C-terminus. Catenin beta-1, also called CTNNB1, is a cytoplasm and nucleus protein of the beta-catenin family. CTNNB1 is a key component of the cadherin cell-cell adhesion system that serves important roles in cell development, differentiation, maintenance of normal tissue architecture, and when dysregulated contributes to tumor invasion and metastasis. The mutations and overexpression of CTNNB1 are associated with many cancers, such as hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors, ovarian and endometrial cancer. CTNNB1 is involved in signal transduction through the Wnt pathway, and is widely expressed in many tissues.
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus, Cytoplasm, Cell junction, Cell junction, Cell membrane, Cytoplasm, Cytoplasm, Cell junction |
| Post transnational modification: | Deacetylated at Lys-49 by SIRT1. |
| BioGrid: | 198512. 79 interactions. |
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