Recombinant Mouse BTLA Protein, His Tag

Product code: 32-17605

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Available Pack Size(s)

  •   100 µg

  •   50 µg

  • $649.00 

  • $527.00 

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Amount : 50 µg
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Uniprot ID : Q7TSA3
Alternative Name : BTLA,CD272
Molecular Characterization: Mouse BTLA(Glu30-Pro176) 6×His tag
Molecular weight: The protein has a predicted molecular mass of 17.4 kDa after removal of the signal peptide.The apparent molecular mass of Mouse-BTLA-His is approximately 35-55 kDa due to glycosylation.
Description: Recombinant mouse BTLA protein with C-terminal 6×His tag
Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed: 12796776, PubMed: 14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed: 19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed: 19915044).
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