Recombinant Human Zinc Finger Protein 762/ZFN762/ZIK1 (N-T7 tag)(Discontinued)

Product code: 32-8189

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Amount : 50 µg
Content : Lyophilized from a 0.2 µm filtered solution of 20mM Tris, pH 7.5.
Storage condition : Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
AA sequence : MASMTGGQQMGRGSMAAAALRAPTQVTVSPETHMDLTKGCVTFEDIAIYFSQDEWGLLDEAQRLLYLEVMLENFALVASLGCGHGTEDEETPSDQNVSVGVSQSKAGSSTQKTQSCEMCVPVLKDILHLADLPGQKPYLVGECTNHHQHQKHHSAKKSLKRDMDRASYVKCCLFCMSLKPFRKWEVGKDLPAMLRLLRSLVFPGGKKPGTITECGEDIRSQKSHYKSGECGKASRHKHTPVYHPRVYTGKKLYECSKCGKAFRGKYSLVQHQRVHTGERPWECNECGKFFSQTSHLNDHRRIHTGERPYECSECGKLFRQNSSLVDHQKIHTGARPYECSQCGKSFSQKATLVKHQRVHTGERPYKCGECGNSFSQSAILNQHRRIHTGAKPYECGQC
Gene : ZIK1
Gene ID : 284307
Uniprot ID : Q3SY52
Source: E. coli.
MW :44.6kD.
Recombinant Human Zinc Finger Protein 762 is produced by our E.coli expression system and the target gene encoding Met1-Cys384 is expressed with a T7 tag at the N-terminus. Zinc Finger Protein Interacting with Ribonucleoprotein K (ZIK1) is a 487 amino acid nuclear protein that belongs to the Krueppel C2H2-Type Zinc-Finger Protein family. ZIK1 has nine C2H2-type zinc fingers and a KRAB domain. This protein is expressed at high levels in the gastric glands and at low levels in the colon and small intestine. It has been shown that ZIK1 is a transcriptional repressor that interacts with the Heterogeneous Nuclear Ribonucleoprotein Particle K Protein (HNRPK).

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Tissue Specificity: Expressed at high levels in gastric glands, and at low levels in colon and small intestine. Silenced through promoter methylation in gastric glands with intestinal metaplasia.
BioGrid: 129823. 1 interactions.
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