Recombinant Human Unconventional SNARE In The ER 1
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Amount : | 10 µg |
Purification : | Greater than 80.0% as determined by SDS-PAGE. |
Content : | USE1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT. |
Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMAASRLE LNLVRLLSRC EAMAAEKRDP DEWRLEKYVG ALEDMLQALK VHASKPASEV INEYSWKVDF LKGMLQAEKL TSSSEKALAN QFLAPGRVPT TARERVPATK TVHLQSRARY TSEMRSELLG TDSAEPEMDV RKRTGVAGSQ PVSEKQSAAE LDLVLQRHQN LQEKLAEEML GLARSLKTNT LAAQSVIKKD NQTLSHSLKM ADQNLEKLKT ESERLEQHTQ KSVN |
Alternative Name : | Vesicle transport protein USE1, Putative MAPK-activating protein PM26, USE1-like protein, p31, USE1L, MDS032, Q-SNARE, SLT1, SNARE-Like Tail-Anchored Protein 1 Homolog, Protein P31. |
Source : Escherichia Coli.
USE1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 254 amino acids (1-231 a.a) and having a molecular mass of 28.3kDa.USE1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
USE1
Belongs to the USE1 family, this protein is a vesicle transport protein. USE1
is a component of a SNARE
complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. In addition
USE1 interacts directly with STX18. SNARE
may be involved
in targeting and fusion of Golgi-derived retrograde transport vesicles with the
ER. Diseases associated with USE1 comprise dysentery and hemolytic-uremic
syndrome. Among its related super-pathways are Nicotine Pathway (Dopaminergic
Neuron) and Pharmacodynamics. GO annotations related to this gene include
protein binding.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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