Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1
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Amount : | 10 µg |
Purification : | "Greater than 80% as determined by SDS-PAGE." |
Content : | TGFBRAP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
AA sequence : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT |
Alternative Name : | TRAP-1, TRAP1, Transforming growth factor-beta receptor-associated protein 1, TGF-beta receptor-associated protein 1. |
Source : Escherichia Coli.
TGFBRAP1 Human Recombinant produced in E.Coli is a
single, non-glycosylated polypeptide chain containing 296 amino acids (601-860 a.a)
and having a molecular mass of 33kDa.TGFBRAP1 is fused to a 36 amino acid His-tag at
N-terminus & purified by proprietary chromatographic techniques.
TGF-beta receptor-associated protein 1 also known
as TGFBRAP1 takes part in the TGF-beta/activin signaling pathway. TGFBRAP1 is
related with inactive heteromeric
TGF-beta and activin receptor complexes, mainly
through the type
II receptor, and is released
upon activation of signaling. TGFBRAP1recruits SMAD4 to the vicinity of the
receptor complex and smoothes the progress of its interaction with
receptor-regulated Smads, such as SMAD2.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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