Recombinant Human TGFBR1 Protein, hFc Tag
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| Amount : | 50 µg |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | P36897 |
| Alternative Name : | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1 |
Molecular Characterization: TGFBR1(Leu34-Leu126) hFc(Glu99-Ala330)
Molecular weight: The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of TGFBR1-hFc is approximately 35-40 kDa due to glycosylation.
Description: Recombinant human TGFBR1 protein with C-terminal Human Fc tag
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular weight: The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of TGFBR1-hFc is approximately 35-40 kDa due to glycosylation.
Description: Recombinant human TGFBR1 protein with C-terminal Human Fc tag
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
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