Recombinant Human TBC1 Domain Family, Member 1
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| Amount : | 20 µg |
| Purification : | "Greater than 90.0% as determined by SDS-PAGE." |
| Content : | TBC1D1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD |
| Alternative Name : | TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1, KIAA1108, TBC, TBC1, TBC1 Domain Family Member 1. |
Source : Escherichia Coli.
TBC1D1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 288 amino acids (1-265 a.a) and having a molecular mass of 33.2kDa.TBC1D1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
TBC1D1
belongs to a family of proteins sharing a 180-200 a.a TBC domain having a role
in regulating cell growth and differentiation of various tissues. These
proteins share significant homology with TRE2, yeast Bub2, and CDC16. TBC1D1
function as a GTPase-activating protein for Rab family proteins. TBC1D1 is
involved in the trafficking and translocation of GLUT4-containing vesicles and
insulin-stimulated glucose uptake into cells. Among the diseases associated
with TBC1D1 are tuberculous meningitis, and meningitis.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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