Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide B
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Amount : | 10 µg |
Purification : | Greater than 90.0% as determined by SDS-PAGE. |
Content : | The SNRPB2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 40% glycerol and 0.1M NaCl. |
Storage condition : | SNRPB2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MDIRPNHTIY INNMNDKIKK EELKRSLYAL FSQFGHVVDI VALKTMKMRG QAFVIFKELG SSTNALRQLQ GFPFYGKPMR IQYAKTDSDI ISKMRGTFAD KEKKKEKKKA KTVEQTATTT NKKPGQGTPN SANTQGNSTP NPQVPDYPPN YILFLNNLPE ETNEMMLSML FNQFPGFKEV RLVPGRHDIA FVEFENDGQA GAARDALQGF KITPSHAMKI TYAKK |
Alternative Name : | Small nuclear ribonucleoprotein polypeptide B2, Msl1, U2 snRNP B'', U2 small nuclear ribonucleoprotein B'', MGC24807, MGC45309. |
Source : Escherichia Coli.
SNRPB2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-225a.a.) and having a molecular mass of 27.6kDa. The SNRPB2 is purified by proprietary chromatographic techniques.
SNRPB2 is a member of the RRM U1 A/B family. SNRPB2 links with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A. SNRPB2 has a part in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus often identify epitopes on the encoded protein. A pair of transcript variants encoding the same protein were identified for this gene.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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