Recombinant Human Secreted Frizzled-Related Protein 2
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| Amount : | 20 µg |
| Purification : | Greater than 85.0% as determined by SDS-PAGE. |
| Content : | SFRP2 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSARGLFLF GQPDFSYKRS NCKPIPVNLQ LCHGIEYQNM RLPNLLGHET MKEVLEQAGA WIPLVMKQCH PDTKKFLCSL FAPVCLDDLD ETIQPCHSLC VQVKDRCAPV MSAFGFPWPD MLECDRFPQD NDLCIPLASS DHLLPATEEA PKVCEACKNK NDDDNDIMET LCKNDFALKI KVKEITYINR DTKIILETKS KTIYKLNGVS ERDLKKSVLW LKDSLQCTCE EMNDINAPYL VMGQKQGGEL VITSVKRWQK GQREFKRISR SIRKLQC. |
| Alternative Name : | FRP-2, SARP1, SDF-5, Secreted frizzled-related protein 2, UNQ361/PRO697, FKSG12, FKSG12. |
Source : Escherichia Coli.
SFRP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 297 amino acids (20-295 a.a) and having a molecular mass of 33.8kDa.SFRP2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Secreted frizzled-related
protein 2 (SFRP2) belongs to the SFRP family which contains a cysteine-rich
domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRP2
function as soluble modulators of Wnt signaling. Methylation of SFRP2 is a
possible marker for the existence of colorectal cancer.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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