Recombinant Human Retinoblastoma Binding Protein 9
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Amount : | 20 µg |
Purification : | Greater than 95% as determined by SDS-PAGE. |
Content : | RBBP9 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 100mM NaCl, 1mM DTT and 10% glycerol. |
Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MASPSKAVIV PGNGGGDVTT HGWYGWVKKE LEKIPGFQCL AKNMPDPITA RESIWLPFME TELHCDEKTI IIGHSSGAIA AMRYAETHRV YAIVLVSAYT SDLGDENERA SGYFTRPWQW EKIKANCPYI VQFGSTDDPF LPWKEQQEVA DRLETKLHKF TDCGHFQNTE FHELITVVKS LLKVPA |
Alternative Name : | Retinoblastoma binding protein 9, RBBP-9, Retinoblastoma-binding protein 10, RBBP-10, BOG, B5T-overexpressed gene protein, putative hydrolase RBBP9, retinoma-binding protein 9. |
Source : E.coli.
RBBP9 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (1-186 a.a.) and having a molecular mass of 23.1kDa.RBBP9 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
RBBP9, restricts to the nucleus and cytoplasm, is a retinoblastoma binding protein which takes part in the regulation of cell proliferation and differentiation. RBBP9 cooperates with retinoblastoma (Rb) and offers cellular resistance to the growth-inhibitory effects of TGFbeta1, therefore enabling the cellular transformation process.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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