Recombinant Human/Rat Neuritin(Discontinued)
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| Amount : | 20 µg |
| Purification : | Purity:>= 98% by SDS-PAGE gel and HPLC analyses. |
| Content : | This recombinant protein is supplied in lyophilized form. |
| AA sequence : | AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN |
Source:E.coliNeuritin is a neurotrophic factor that is expressed in response to the induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system, and in neuronal structures related to synaptic plasticity in the adult nervous system.  Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.  Recombinant Human/Rat Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.
Determined by a cell proliferation using rat C6 cells. The ED50for this effect is 20.0-30.0 ng/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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