Recombinant human PVRIG protein with C-terminal human Fc tag
Figure 1. Human PVRIG Protein, hFc Tag on SDS-PAGE under reducing condition.
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| Amount : | 50 µg |
| Purification : | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Alternative Name : | C7orf15, CD112R |
Expression Host : HEK293
The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation.
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.AO152:AO169.
The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation.
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.AO152:AO169.
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