Recombinant Human Profilin-4
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| Amount : | 25 µg |
| Purification : | Greater than 95% as determined by SDS-PAGE. |
| Content : | PFN4 Human solution containing 20mM Trsi HCL pH-8, 1mM DTT and 10% glycerol. |
| Storage condition : | PFN4 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MSHLQSLLLD TLLGTKHVDS AALIKIQERS LCVASPGFNV TPSDVRTLVN GFAKNPLQAR REGLYFKGKD YRCVRADEYS LYAKNENTGV VVVKTHLYLL VATYTEGMYP SICVEATESL GDYLRKKGS. |
| Alternative Name : | PFN-4, Profilin-IV, Profilin4. |
Source : Escherichia Coli.
PFN4 Human Recombinant produced in E.Coli is a single, non-glycosylated,
polypeptide chain containing 149 amino acids (1-129 a.a.) and having a molecular mass of 16.4 kDa. PFN4 protein is fused to a 20 amino acid His tag at N-terminus and purified by standard chromatography.
PFN4 is a small actin-binding protein that participates in the dynamic turnover and restructuring of the actin cytoskeleton. PFN4 is localized in all eukaryotic organisms in the majority of cells. PFN4 is crucial for spatially and temporally controlled growth of actin microfilaments, which is a necessary process in cellular locomotion and cell shape changes.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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