Recombinant Human PPT1 Protein, His Tag
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Amount : | 50 µg |
Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Uniprot ID : | P50897 |
Alternative Name : | CLN1; PPT |
Molecular Characterization: PPT1(Asp28-Gly306) 6×His tag
Molecular weight: The protein has a predicted molecular mass 32.1 of kDa after removal of the signal peptide. The apparent molecular mass of PPT1-His is approximately 33-40 kDa due to glycosylation.
Description: Recombinant human PPT1 protein with C-terminal 6×His tag
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
Molecular weight: The protein has a predicted molecular mass 32.1 of kDa after removal of the signal peptide. The apparent molecular mass of PPT1-His is approximately 33-40 kDa due to glycosylation.
Description: Recombinant human PPT1 protein with C-terminal 6×His tag
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
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