Recombinant Human PlGF-2(Discontinued)
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| Amount : | 25 µg |
| Purification : | Purity: >= 95% by SDS-PAGE gel and HPLC analyses. |
| Content : | This recombinant protein is supplied in lyophilized form. |
| AA sequence : | LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR |
| Alternative Name : | Placenta Growth Factor-2, PGFL |
Source:E.coli
PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors.   PlGF-2 is expressed  in umbilical vein endothelial cells and placenta.   It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration.   PlGF-2 also signals through Neuropilin (NP-1), and can bind with  high affinity to heparin. Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains.
PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors.   PlGF-2 is expressed  in umbilical vein endothelial cells and placenta.   It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration.   PlGF-2 also signals through Neuropilin (NP-1), and can bind with  high affinity to heparin. Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains.
Determined by its ability to chemoattract human THP-1 cells of using a concentration range of 5.0-50.0 ng/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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