Recombinant Human Peroxisomal Acyl-coenzyme A Oxidase 1/ACOX1 (N-6His)(Discontinued)
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| Amount : | 50 µg |
| Content : | Supplied as a 0.2 µm filtered solution of 20mM Tris, 500mM NaCl, pH7.0, 20% gly, 3mM DTT . |
| Storage condition : | Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHHSSGLVPRGSHMNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEMKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL |
Source: E.coli.
MW :76.8kD.
Recombinant Human Peroxisomal Acyl-coenzyme A oxidase 1 is produced by our expression system and the target gene encoding Met1-Leu660 is expressed with a 6His tag at the N-terminus. Peroxisomal acyl-coenzyme A oxidase 1 is an enzyme belongs to the acyl-CoA oxidase family. It catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. it is involved in the pathway peroxisomal fatty acid beta-oxidation, which is part of Lipid metabolism. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.
MW :76.8kD.
Recombinant Human Peroxisomal Acyl-coenzyme A oxidase 1 is produced by our expression system and the target gene encoding Met1-Leu660 is expressed with a 6His tag at the N-terminus. Peroxisomal acyl-coenzyme A oxidase 1 is an enzyme belongs to the acyl-CoA oxidase family. It catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. it is involved in the pathway peroxisomal fatty acid beta-oxidation, which is part of Lipid metabolism. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Peroxisome |
| Tissue Specificity: | Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart. |
| BioGrid: | 106567. 44 interactions. |
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