Recombinant Human Paired Related Homeobox 1
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| Amount : | 10 µg |
| Purification : | Greater than 85.0% as determined by SDS-PAGE. |
| Content : | PRRX1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F |
| Alternative Name : | AGOTC, PHOX1, PMX1, PRX-1, PRX1, Paired mesoderm homeobox protein 1, Homeobox protein PHOX1, Paired-related homeobox protein 1, PRRX1. |
Source : Escherichia Coli.
PRRX1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 241 amino acids (1-217 a.a) and having a molecular mass of 26.9kDa.PRRX1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
PRRX1
is part of the paired family of homeobox proteins. PRRX1 functions as a
transcription co-activator, enhancing the DNA-binding activity of serum response
factor, a protein required for the induction of genes by growth and
differentiation factors. PRRX1 also regulates muscle creatine kinase, and
therefore has a part in the establishment of diverse mesodermal muscle types. The
protein binds to an A/T-rich element in the muscle creatine enhancer. Among the
diseases associated with PRRX1 are agnathia-otocephaly complex, and pleomorphic
liposarcoma.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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