Recombinant Human NT-3(Discontinued)

Product code: 32-20318

Reactivity : Chicken, Cow, Dog, Human, Monkey, Mouse, Pig, Rat

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Alternative Name : Neurotrophin-3, Neurotrophic factor, Nerve growth factor-2, NGF-2, HGNF
Source:E.coli
NT-3 is a neurotrophic factor structurally related to Beta-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous system, and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant Human NT-3 is a noncovalently linked homodimer of two 13.6 kDa polypeptide monomers (240 total amino acid residues).

The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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