Recombinant Human Modulator Of Apoptosis 1
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Amount : | 20 µg |
Purification : | "Greater than 85% as determined by SDS-PAGE." |
Content : | MOAP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMTLRLLE DWCRGMDMNP RKALLIAGIS QSCSVAEIEE ALQAGLAPLG EYRLLGRMFR RDENRKVALV GLTAETSHAL VPKEIPGKGG IWRVIFKPPD PDNTFLSRLN EFLAGEGMTV GELSRALGHE NGSLDPEQGM IPEMWAPMLA QALEALQPAL |
Alternative Name : | Modulator Of Apoptosis 1, MAP1, PNMA4, Paraneoplastic Ma Antigen Family Member 4, Paraneoplastic Antigen Ma4, MAP-1, Paraneoplastic Antigen Like 4. |
Source : Escherichia Coli.
MOAP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 374 amino acids (1-351a.a) and having a molecular mass of 41.9kDa.MOAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Modulator
of apoptosis 1 (MOAP1), is a member of the PNMA family and contains one BH3-like domain
and one RASSF1-binding domain. MOAP1 was recognized by its interaction with
apoptosis regulator BAX protein. MOAP1 includes a Bcl-2 homology 3 (BH3)-like
motif, which is essential for the association with BAX. In addition, once over
expressed MOAP1 mediates caspase-dependent apoptosis.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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