Recombinant Human MIP-3 (CCL23)(Discontinued)
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Amount : | 20 µg |
Purification : | Purity: >= 98% by SDS-PAGE gel and HPLC analyses. |
Content : | This recombinant protein is supplied in lyophilized form. |
AA sequence : | RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN |
Alternative Name : | Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck- Beta8 |
Source:E.coli
MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes, and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant Human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes, and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant Human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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