Recombinant Human LSM5 Homolog, U6 Small Nuclear RNA Associated
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| Amount : | 20 µg |
| Purification : | Greater than 95.0% as determined by SDS-PAGE. |
| Content : | LSM5 protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.5), 10% glycerol, 0.15M NaCl and 1mM DTT. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMAANATT NPSQLLPLEL VDKCIGSRIH IVMKSDKEIV GTLLGFDDFV NMVLEDVTEF EITPEGRRIT KLDQILLNGN NITMLVPGGE GPEV |
| Alternative Name : | LSM5 homolog, U6 small nuclear RNA associated (S.cerevisiae), YER146W, U6 snRNA-associated Sm-like protein LSm5. |
Source : Escherichia Coli.
LSM5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (1-91 a.a) and having a molecular mass of 12.3kDa.LSM5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
LSM5
also known as LSM5 Homolog, U6 Small Nuclear RNA Associated belongs to the Sm
protein family. This family is identified in a variety of organisms
based on sequence homology. Sm-like proteins contain the Sm sequence motif,
which consists of 2 regions separated by a linker of variable length which
folds as a loop. In addition, the Sm-like proteins are thought to create a
stable heteromer present in tri-snRNP
particles, which are important for pre-mRNA splicing. Among the diseases
associated with LSM5 are spinal muscular atrophy, and muscular atrophy.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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