Recombinant Human Lck Interacting Transmembrane Adaptor 1 (Discontinued)
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| Amount : | 20 µg |
| Purification : | Greater than 80% as determined by SDS-PAGE. |
| Content : | LIME1 protein solution (0.5 mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSCTACRRP EDAVAPRKRA RRQRARLQGS ATAAEASLLR RTHLCSLSKS DTRLHELHRG PRSSRALRPA SMDLLRPHWL EVSRDITGPQ AAPSAFPHQE LPRALPAAAA TAGCAGLEAT YSNVGLAALP GVSLAASPVV AEYARVQKRK GTHRSPQEPQ QGKTEVTPAA QVDVLYSRVC KPKRRDPGPT TDPLDPKGQG AILALAGDLA YQTLPLRALD VDSGPLENVY ESIRELGDPA GRSSTCGAGT PPASSCPSLG RGWRPLPASL P |
| Alternative Name : | Lck-Interacting Membrane Protein, Lck-Interacting Molecule, Lck-Interacting Transmembrane Adapter, LP8067, dJ583P15. |
Source : Escherichia Coli. LIME1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 291 amino acids (28-295a.a) and having a molecular mass of 30.8kDa. LIME1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Lck-interacting transmembrane adapter 1 precursor (LIME1) is a transmembrane adaptor protein which is preferentially expressed in hemopoietic cells, mainly T cells. LIME1 mediates TCR-dependent T cell activation, additionally LIME1 becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 co receptors. The inflammatory bowel disease is associated with LIME1.
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