Recombinant Human LAIR1 (C-mFc)
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 50 µg |
| Content : | Lyophilized from a 0.2 um filtered solution of 2umM PB, 15umM NaCl, pH 7.2 |
| AA sequence : | Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 1 is produced by human 293 cells. The target gene encoding Gln22-Tyr165 is expressed with a 6His tag at the C-terminus. |
| Alternative Name : | Leukocyte-Associated Immunoglobulin-Like Receptor 1; LAIR-1; hLAIR1; CD305 |
Source : Human 293 Cells;
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is a type I transmembrane glycoprotein, that belongs to immunoglobulin superfamily and leukocyte-associated inhibitory receptor family. LAIR-1 is expressed on most of the mononuclear cells, including natural killer (NK) cells, B-cells, T-cells, monocytes, and dendritic cells. LAIR-1 plays a role in negatively regulating the cytolytic function of immune cells to prevent lysis of cells recognized as self. Studies predicted that LAIR-1 mediates the inhibitory function based on immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic domain.
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is a type I transmembrane glycoprotein, that belongs to immunoglobulin superfamily and leukocyte-associated inhibitory receptor family. LAIR-1 is expressed on most of the mononuclear cells, including natural killer (NK) cells, B-cells, T-cells, monocytes, and dendritic cells. LAIR-1 plays a role in negatively regulating the cytolytic function of immune cells to prevent lysis of cells recognized as self. Studies predicted that LAIR-1 mediates the inhibitory function based on immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic domain.
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
