Recombinant Human KCNMB3
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| Amount : | 20 µg |
| Purification : | "Greater than 85.0% as determined by SDS-PAGE." |
| Content : | KCNMB3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQV FVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSED VILIKKYDQ. |
| Alternative Name : | Potassium Channel Subfamily M Regulatory Beta Subunit 3, Potassium Large Conductance Calcium-Activated Channel, Subfamily M Beta Member 3, Calcium-Activated Potassium Channel, Subfamily M Subunit Beta-3, Charybdotoxin Receptor Subunit Beta-3, Big Pot |
Source : Escherichia Coli.
KCNMB3 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 149 amino acids (82-207 a.a) and
having a molecular mass of 16.8kDa.
KCNMB3 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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