Recombinant Human ITGB1 Protein, hFc Tag
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Amount : | 50 µg |
Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Uniprot ID : | P05556 |
Alternative Name : | GPIIA, CD29, VLA-4 subunit beta |
Molecular Characterization: ITGB1(Gln21-Asp728) hFc(Glu99-Ala330)
Molecular weight: The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGB1-hFc is approximately 130-250 kDa due to glycosylation.
Description: Recombinant human ITGB1 protein with C-terminal human Fc tag
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Molecular weight: The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGB1-hFc is approximately 130-250 kDa due to glycosylation.
Description: Recombinant human ITGB1 protein with C-terminal human Fc tag
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
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