Recombinant Human IL-33(Discontinued)
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Amount : | 10 µg |
Purification : | Purity:>= 98% by SDS-PAGE gel and HPLC analyses. |
Content : | This recombinant protein is supplied in lyophilized form. |
AA sequence : | SITGISPITE YLASLSTYND QSITFALEDE SYEIYVEDLK KDEKKDKVLL SYYESQHPSN ESGDGVDGKM LMVTLSPTKD FWLHANNKEH SVELHKCEKP LPDQAFFVLH NMHSNCVSFE CKTDPGVFIG VKDNHLALIK VDSSENLCTE NILFKLSET |
Alternative Name : | Interleukin-33, IL-1 F11, NF-HEV |
Source:E.coliHuman IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, to activate NF-kB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant Human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is <=0.05 ng/ml, corresponding to a specific activity of>= 2 x 107units/mg.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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