Recombinant Human IL-10(Discontinued)

Product code: 32-20433

Reactivity : Human, Monkey, Mouse, Virus

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity:>= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
Alternative Name : B-TCGF, CSIF, TGIF
Source:E.coli
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes.  IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-Alpha .  Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions.  Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells.  Recombinant Human IL-10 is an 18.6 kDa protein of 161 amino acid residues.

Determined by the dose-dependent co-stimulation (with human IL-4) of MC/9 cells. The ED50 was found to be <=2.0 ng/ml, corresponding to a specific activity of>= 5 x 105 units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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