Recombinant Human IGF-BP2(Discontinued)

Product code: 32-20659

Reactivity : Human, Mouse

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For estimated delivery dates, please contact us at [email protected]


Amount : 20 µg
Purification : Purity:>= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
Alternative Name : Insulin-like Growth Factor-Binding Protein 2, IBP-2
Source:(BTI-Tn-5B1-4) Hi-5 Insect cells
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids.  Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II.  IGF-BP2 is a cysteine-rich, secreted protein produced by bone cells, and is most abundant in the brain.  IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells.  Recombinant Human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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