Recombinant human IGF-1R protein with C-terminal human Fc tag

Product code: 32-17174

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50 µg
$498.00 

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Amount : 50 µg
Purification : The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage condition : Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : IGF1R,IGFR,JTK13,CD221,MGC142170,MGC142172,MGC18216
Expression Host : HEK293
The protein has a predicted molecular mass of 124.74 kDa after removal of the signal peptide.
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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