Recombinant Human IFNA1 Protein, hFc Tag
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| Amount : | 50 µg |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | P01562 |
| Alternative Name : | IFN-alpha-1/13, LeIF D, IFNA13 |
Molecular Characterization: IFNA1(Cys24-Glu189) hFc(Glu99-Ala330)
Molecular weight: The protein has a predicted molecular mass of 45.5 kDa after removal of the signal peptide. The apparent molecular mass of IFNA1-hFc is approximately 35-55 kDa due to glycosylation.
Description: Recombinant human IFNA1 protein with C-terminal human Fc tag
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
Molecular weight: The protein has a predicted molecular mass of 45.5 kDa after removal of the signal peptide. The apparent molecular mass of IFNA1-hFc is approximately 35-55 kDa due to glycosylation.
Description: Recombinant human IFNA1 protein with C-terminal human Fc tag
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
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