Recombinant Human Histatin-3/HTN3
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Amount : | 50 µg |
Content : | Supplied as a 0.2 µm filtered solution of PBS, pH 7.4. |
Storage condition : | Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
AA sequence : | GHMDSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN |
Source: E. coli.
MW :4.4kD.
Recombinant Human Histatin-3 is produced by our E.coli expression system and the target gene encoding Asp20-Asn51 is expressed. Histatin-3(HTN3) belongs to the histatin/statherin family. Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Post-translational proteolytic processing results in many histatins: e.g., histatins 4-6 are derived from histatin 3 by proteolysis. Histatins 1 and 3 are primary products of HIS1and HIS2 alleles, respectively. Histatins are believed to have important non-immunological, anti-microbial function in the oral cavity. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9.
MW :4.4kD.
Recombinant Human Histatin-3 is produced by our E.coli expression system and the target gene encoding Asp20-Asn51 is expressed. Histatin-3(HTN3) belongs to the histatin/statherin family. Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Post-translational proteolytic processing results in many histatins: e.g., histatins 4-6 are derived from histatin 3 by proteolysis. Histatins 1 and 3 are primary products of HIS1and HIS2 alleles, respectively. Histatins are believed to have important non-immunological, anti-microbial function in the oral cavity. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9.
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Secreted |
Post transnational modification: | 24 proteolytic products are found in saliva. |
BioGrid: | 109579. 1 interactions. |
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