Recombinant Human GDF-2(Discontinued)

Product code: 32-20562

Reactivity : Human, Mouse

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Amount : 10 µg
Purification : Purity:>= 95% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : SAGAGSHCQK TSLRVNFEDI GWDSWIIAPKE YEAYECKGGC FFPLADDVTPTK HAIVQTLVHL KFPTKVGKAC CVPTKLSPIS VLYKDDMGVP TLKYHYEGMS VAECGCR
Alternative Name : Growth/Differentiation Factor-2, BMP-9
Source:CHO cells
GDF-2 belongs to the TGF-Beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a 24.1 kDa disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9 ng/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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